10 Best Apigenin Supplements in 2026

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The best overall apigenin supplement is Double Wood Supplements Apigenin Capsules, which wins for its NSF-certified manufacturing and straightforward two-month supply. For premium purity, consider the Momentous Apigenin Supplement Capsules, while those seeking a high dose may prefer Nootropics Depot Apigenin Capsules. Many users look to apigenin, a natural flavonoid from chamomile, for its studied role in supporting relaxation and sleep quality without heavy sedation.

The challenge is finding a supplement with the right dose, purity, and delivery method for your specific protocol. This guide is based on research into specifications, manufacturing standards, and patterns in user feedback across ten top options, helping you select a product that matches your priorities.

Top 10 Apigenin Supplements in the Market

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The Best Apigenin Supplements, Reviewed

#1Best Overall

Double Wood Supplements Apigenin Capsules

Double Wood Supplements Apigenin Capsules
Dosage per capsule50mg
Capsules per bottle120
Supply durationTwo months
Third-party testingNSF Certified
Key certificationsNon-GMO, Gluten-Free
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What We Like

  • NSF certification ensures manufacturing quality
  • Two-month supply reduces reorder frequency
  • Non-GMO and gluten-free formulation
  • Third-party tested for ingredient verification

Trade-offs

  • 50mg dose is lower than some 200mg competitors

A 120-capsule bottle provides a full two-month supply, which simplifies the routine for someone building a consistent, long-term protocol. The NSF certification is the concrete signal that cuts through supplement industry noise; it means the contents match the label and the manufacturing facility meets stringent standards. For the skeptical tinkerer, that’s the foundational piece you need before you even consider a substance’s purported benefits. This combination of sensible duration and verifiable quality makes it a reliable cornerstone for testing apigenin’s effects on relaxation or cognitive support.

The trade-off is the straightforward 50mg dose, which is a quarter of what you get in a capsule from something like Nootropics Depot. That’s fine for starting a protocol or for those sensitive to new supplements, but it leaves you taking more capsules if you’re aiming for the higher end of researched doses. It also doesn’t employ any specialized delivery systems, so if enhanced bioavailability is your primary concern, you’d look at the liposomal options from brands like Toniiq or Codeage. This is the no-nonsense, well-bottled baseline.

Best for: Skeptical users who prioritize verified manufacturing quality and a simple, two-month supply for consistent protocol testing. Not ideal for those seeking the highest per-capsule dose or advanced delivery technology.

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#2Best Premium Brand

Momentous Apigenin Supplement Capsules

Momentous Apigenin Supplement Capsules
Serving Size1 capsule
Apigenin per Serving50mg
CertificationNSF Certified for Sport
Servings per Container60
Primary UseSleep support
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What We Like

  • NSF Certified for Sport for trusted purity
  • 50mg dose timed 30-60 minutes before sleep
  • Formulated with expert scientific input
  • Non-GMO and gluten-free

Trade-offs

  • 50mg dose is lower than some competitors' offerings

The NSF Certified for Sport stamp means every batch is tested for banned substances and contaminants, a critical feature for competitive athletes or anyone who gets drug tested. Momentous delivers a straightforward 50mg of apigenin, a dose positioned to support relaxation and higher-quality sleep by calming neuronal activity. It suits the buyer who prioritizes verified purity and a clean, single-ingredient approach over a complex blend, trusting the brand’s collaboration with performance scientists.

Momentous offers a 50mg dose of apigenin per capsule, which is one-quarter the amount found in Nootropics Depot’s 200mg option, making it a more moderate entry point for sleep support. Their minimalist formula focuses solely on this single ingredient, so users wanting a blend with magnesium or L-theanine would need to consider a multi-ingredient product like Earth Elixir’s sleep aid. The brand’s NSF Certified for Sport status provides assurance for athletes concerned about banned substances, a certification that some budget options like Double Wood Supplements lack.

Best for: Competitive athletes and purity-focused users seeking a trusted, single-ingredient sleep aid. Not ideal for those seeking the highest apigenin dose per capsule or a multi-ingredient relaxation blend.
#3Best High-Purity Formula

Nootropics Depot Apigenin Capsules

Nootropics Depot Apigenin Capsules
Apigenin per capsule200mg
Purity>98% Apigenin
Capsule count30 Count
Key benefitSupports healthy stress levels
Quality verificationLab tested and verified
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What We Like

  • Exceptionally high 200mg dose per capsule
  • Greater than 98% purity level
  • Lab-tested for ingredient strength and purity

Trade-offs

  • Only 30 capsules per bottle.
  • Single ingredient, no blends.

A 200mg dose of >98% pure apigenin is the decisive fact here. That’s a clinical-strength serving in a single capsule, which means you’re getting a concentrated, no-frills formula aimed at delivering the researched benefits, like supporting memory cells and blocking the CD38 enzyme, without filler.

The bottle only contains 30 capsules, which gives you a one-month trial at the full dose. Many other brands, like Double Wood, offer 120 capsules for a longer protocol. If your goal is to pair apigenin with something like L-Theanine for sleep, you’d need a separate supplement, unlike the ready-made combination in Sundial’s offering. For pure, high-dose apigenin from a brand focused on nootropics, this is the pick. For a longer-running or multi-ingredient approach, you’d look elsewhere.

Best for: The user prioritizing a high-dose, high-purity single-ingredient apigenin supplement. Not ideal for someone wanting a long-supply bottle or a pre-blended formula with complementary ingredients.

Product photos

#4Best High-Strength Liposomal

Toniiq Liposomal Apigenin Capsules

Toniiq Liposomal Apigenin Capsules
FormLiposomal capsules
Serving size100mg apigenin
Capsule count180 vegetarian capsules
ManufacturingGMP-certified US facility
TestingBatch-tested, third-party verified
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What We Like

  • Liposomal delivery for enhanced absorption
  • High 100mg dose per capsule
  • Rigorous batch and purity testing
  • Large 180-capsule supply

Trade-offs

  • No independent certification like NSF

Toniiq’s 100mg liposomal apigenin directly tackles the absorption challenge common with this flavonoid, so buyers seeking its studied benefits can focus on bioavailability rather than just dose size. The product is manufactured in a GMP-certified U.S. facility with each batch tested in-house and by a third-party lab for purity, which provides a clear standard for quality assurance.

Unlike Momentous or Double Wood supplements, this product lacks an NSF certification, a tangible difference for athletes or those with strict purity requirements. Its 100mg strength is lower than Nootropics Depot’s 200mg capsule, but the liposomal delivery system is designed to enhance absorption where other high-dose supplements may fall short.

Best for: Bioavailability-focused supplement users who prioritize absorption technology and manufacturing transparency. Not ideal for athletes requiring NSF Sport certification or those seeking the absolute highest milligram count per capsule.

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#5Best Liposomal Delivery

Codeage Liposomal Apigenin Supplement

Codeage Liposomal Apigenin Supplement
Apigenin per Capsule50 mg
Capsules per Bottle90
Supply Duration3 months
Delivery TechnologyLiposomal phospholipid complex
Key CertificationNSF Certified
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What We Like

  • Liposomal delivery for enhanced absorption
  • Non-GMO, vegan, and gluten-free formula
  • Manufactured in a cGMP-certified U.S. facility

Trade-offs

  • A 3-month supply is shorter than several 4-month competitors
  • Only one serving size option is available

A liposomal phospholipid complex delivers the 50 mg of apigenin per capsule, a formulation focused on bioavailability rather than just raw potency. This approach addresses absorption challenges common with flavonoids, making it a logical option for buyers who value efficient delivery systems. The vegan, non-GMO supplement is NSF Certified and manufactured in a cGMP facility, which signals a commitment to quality and purity standards.

With 90 capsules providing a three-month supply at one per day, the bottle offers a moderate-length regimen. Other products like Double Wood provide 120 capsules for a longer supply at the same 50 mg dose, while options like Nootropics Depot offer 200 mg per capsule. The formulation’s focus is its liposomal delivery technology and certified manufacturing process.

Best for: The bioavailability-focused supplement user who prefers a clean, liposomal-formulated apigenin. Not ideal for those seeking the highest single-serving dose or the longest supply per bottle.
#6Best for Bioavailability

Teaveli Apigenin Supplement with Resveratrol

Teaveli Apigenin Supplement with Resveratrol
Key Ingredient50mg Apigenin
Bioavailability EnhancerResveratrol
Capsule Count120 capsules
Third-Party TestingISO-certified lab
CertificationsPETA-certified, Vegan
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What We Like

  • Resveratrol increases apigenin bioavailability by up to 239%
  • Dose aligns with a popular expert sleep protocol
  • Third-party tested for heavy metals and microbes
  • Plastic-neutral, vegan, and free of major allergens

Trade-offs

  • Bottle is 4.4 inches tall, taller than some competitors
  • No sport-specific certification like NSF for Sport

Combining apigenin with resveratrol can increase apigenin’s bioavailability by up to 2.39 times, directly addressing its known absorption challenge. This product provides a 50mg dose of apigenin, which matches a specific recommendation for sleep support. The formulation is for someone who prioritizes the science of absorption and wants to add this specific dose to a custom supplement regimen.

This is a targeted two-ingredient formula for apigenin absorption, unlike multi-ingredient blends such as Earth Elixir’s sleep aid that includes magnesium and L-theanine. It allows you to add apigenin separately if you already use other sleep-support supplements. The bottle is a compact cylinder, measuring just over four inches tall, which takes up minimal shelf space.

Best for: Someone following a specific 50mg apigenin recommendation and prioritizing its absorption. Not ideal for someone seeking a single-capsule, multi-ingredient sleep solution or requiring NSF for Sport certification.

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#7Best Multi-Ingredient Sleep Formula

Earth Elixir Melatonin-Free Sleep Aid

Earth Elixir Melatonin-Free Sleep Aid
Apigenin per serving100mg
Key additional ingredientsMagnesium glycinate, L-theanine
Other herbal extractsLemon balm, magnolia bark
Melatonin contentNone
CertificationsGMP-certified facility, third-party tested
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What We Like

  • Multi-ingredient formula for comprehensive sleep support
  • Melatonin-free design avoids next-day grogginess
  • Uses highly bioavailable magnesium glycinate
  • Clean, vegan-friendly formulation with third-party testing

Trade-offs

  • Formula complexity may complicate individual ingredient dosing
  • Contains magnolia bark, an herb not in all sleep stacks

A 100mg dose of apigenin is paired with four other clinically-noted sleep ingredients, making this a complete, melatonin-free system for someone who wants a single capsule to address multiple pathways to relaxation. It suits the tinkerer who’s tried single ingredients like magnesium or L-theanine alone and wants a synergistic stack without the guesswork, particularly if they are sensitive to melatonin’s lingering effects.

Its apigenin content is half that of a dedicated high-potency option like Nootropics Depot’s 200mg capsules. This makes it less ideal for someone targeting apigenin’s specific benefits at a maximal dose. For a simpler, two-ingredient approach focused purely on apigenin and L-theanine, Sundial Supplements’ formula offers a higher dose of both, but lacks the herbal extracts and magnesium.

Best for: The supplement user seeking a comprehensive, all-in-one melatonin-free sleep stack that combines apigenin with magnesium and calming herbs. Not ideal for someone wanting to megadose apigenin alone or minimize herbal ingredients.

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#8Best Two-Ingredient Formula

Sundial Supplements Apigenin with L-Theanine

Sundial Supplements Apigenin with L-Theanine
Apigenin per serving200mg
L-Theanine per serving600mg
Capsules per bottle90
Servings per bottle45
Capsule typeVegan cellulose
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What We Like

  • High 200mg dose of apigenin per serving
  • Synergistic 600mg of L-theanine included
  • Clean, two-ingredient formula with no proprietary blends

Trade-offs

  • Requires two capsules for a single serving

Sundial’s formula delivers 200mg of apigenin and 600mg of L-theanine per serving, a specific combination in a straightforward two-ingredient format. This clean label clearly identifies each active amount, avoiding proprietary blends for those who want precise control over these particular compounds.

Unlike some competitors, this formula combines both apigenin and L-theanine, whereas options like Nootropics Depot offer 200mg of apigenin alone. The trade-off is a two-capsule serving, making it a focused tool rather than a single-capsule solution.

Best for: Buyers seeking a transparent, two-ingredient combination of apigenin and L-theanine.

Product photos

#9Best 4-Month Supply

BOSCENT Apigenin 100mg Supplement

BOSCENT Apigenin 100mg Supplement
Apigenin per Capsule100mg
Purity98% pure chamomile extract
Capsule Count120 capsules
Supply Duration4 month supply
Key CertificationsGMP certified, Non-GMO, Vegan
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What We Like

  • High 100mg dose per capsule
  • No proprietary blends or fillers
  • Long 4-month supply in one bottle
  • GMP certified and made in the USA

Trade-offs

  • Standard capsule, not liposomal for absorption
  • One capsule per day for 4-month supply

A 120-capsule bottle provides a full four-month supply at the standard one-capsule daily dose. That bulk offering is the main practical advantage, simplifying the routine for anyone who values consistency and dislikes reordering supplements frequently. The 100mg dose is also on the higher end for a single capsule. It is derived from a stated 98% pure chamomile extract with no fillers, which appeals to the skeptic who wants to know exactly what they’re taking. This is a straightforward, no-nonsense option for building a long-term nightly habit aimed at relaxation and sleep support.

BOSCENT uses a standard capsule format rather than a liposomal one like Codeage or Toniiq, relying on the body’s natural absorption. Its 98% pure chamomile extract provides a single-ingredient formula, unlike Sundial’s blend with L-Theanine, allowing users to pair it with separate supplements as suggested on the label.

Best for: The buyer seeking a high-dose, single-ingredient apigenin supplement in a convenient long-term supply, who prefers to control their own supplement stack. Not ideal for those seeking advanced bioavailability formulas or all-in-one sleep blends.

Product photos

#10Best Clean & Simple Formula

Vitamatic Apigenin Capsules

Vitamatic Apigenin Capsules
Apigenin per Capsule50 mg
Capsules per Bottle120
SourceChamomile-derived
Capsule TypeVegetarian
ManufacturingUSA, GMP-compliant
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What We Like

  • Clean formula free from major allergens and additives.
  • Provides a precise 50 mg dose for consistent daily use.
  • 120-capsule supply supports a long-term routine.
  • Vegetarian capsules suit common dietary preferences.

Trade-offs

  • Lacks third-party certification like NSF
  • Standard 50mg dose is half the potency of some high-strength rivals

A 50 mg dose of chamomile-derived apigenin in a clean, allergen-free capsule makes this a straightforward choice for someone starting a protocol. The four-month supply and simple ingredient list mean you can introduce it without worrying about fillers or artificial additives. This is ideal for the tinkerer who wants to isolate this flavonoid’s effects before stacking it with other supplements. It suits the minimalist who prioritizes a no-nonsense foundation for relaxation or sleep support over a complex blend.

The simplicity is also the trade-off. You’re getting apigenin and nothing else, which means no enhanced absorption technology like the liposomal forms from Toniiq or Codeage. For someone seeking a higher single-serving dose or a formula with synergistic ingredients like the apigenin-resveratrol pairing in Teaveli, this bottle will feel basic. It’s a pure play on the core compound, which is its greatest strength and its most obvious limitation.

Best for: The supplement minimalist seeking a clean, single-ingredient apigenin to test in their protocol. Not ideal for those wanting a high-potency dose or a formula with enhanced bioavailability.

How We Evaluated Apigenin Supplements

We reviewed product specifications, manufacturer documentation, and expert round-ups to compare key factors for this category. The most important criteria were dose per serving, the presence of third-party quality verification like NSF certification, and formulation details like liposomal delivery or complementary ingredients that affect bioavailability. We also considered supply length and value for a consistent daily routine.

This guide is compiled from product specifications and published information. It highlights consistent themes in user-reported experiences with sleep support and quality, though individual outcomes differ. The focus is on verifiable pre-purchase details, such as testing protocols and ingredient clarity.

What To Look For In Apigenin Supplements

Choosing an apigenin supplement involves more than just the milligram count on the label. Your goals for sleep support, bioavailability, and supplement simplicity will determine which product fits your routine.

Key criteria include the apigenin dose per serving, independent quality certifications, and the formulation’s delivery method. Also consider whether you want a single-ingredient product or a blend with complementary ingredients like L-theanine or resveratrol.

Dose and Serving Size

Apigenin supplements offer a wide range of potencies, from 50mg to 200mg per capsule. A standard starting dose in many apigenin sleep supplements is 50mg, taken 30-60 minutes before bed. Higher doses, like 100mg or 200mg, may be sought by those following specific protocols, but they can be more sedating. Always check the serving size, some products require two capsules to reach the listed dose.

Quality Verification and Purity

Independent verification is crucial for trusting what’s in the bottle. Look for third-party testing certifications like NSF Contents Certified or NSF Certified for Sport, which confirm the product contains what the label claims and is free from contaminants. Some brands provide openly published Certificates of Analysis (COAs) for each batch. High-purity claims, such as “greater than 98%,” are also a strong indicator of a quality-focused manufacturer.

Formulation and Bioavailability

Apigenin is a fat-soluble compound, so taking it with food can aid absorption. Some formulas use liposomal delivery technology, which encapsulates the apigenin in phospholipids to enhance its bioavailability. Others combine apigenin with ingredients shown to increase its absorption, like resveratrol, or with synergistic calming agents like L-theanine. A single-ingredient capsule offers the most control for testing apigenin’s individual effects, while multi-ingredient blends provide an all-in-one solution.

  • Check if the capsule is vegetarian or vegan if that aligns with your preferences.
  • Review the full ingredient list for allergens or additives if you follow a restrictive diet.
  • Consider whether you want a product that is non-GMO and gluten-free.
  • Note if the formula uses a proprietary blend, which obscures individual ingredient amounts.
  • Assess the total supply (e.g., 60 vs. 180 capsules) for value and convenience.

The most important choice is between a verified, simple formula for testing and a more complex, bioavailability-focused blend for enhanced effects.

Apigenin Supplements Compared

The following table compares the key specifications of our top-ranked apigenin supplements at a glance.

ProductApigenin per ServingCapsules per BottleThird-Party Testing/Certification
Double Wood Supplements Apigenin Capsules50mg120NSF Certified
Momentous Apigenin Supplement Capsules50mg60NSF Certified for Sport
Nootropics Depot Apigenin Capsules200mg30Lab tested and verified
Toniiq Liposomal Apigenin Capsules100mg180Batch-tested, third-party verified
Codeage Liposomal Apigenin Supplement50 mg90NSF Certified
Teaveli Apigenin Supplement with Resveratrol50mg120ISO-certified lab
Earth Elixir Melatonin-Free Sleep Aid100mgN/Athird-party tested
Sundial Supplements Apigenin with L-Theanine200mg90N/A
BOSCENT Apigenin 100mg Supplement100mg120GMP certified
Vitamatic Apigenin Capsules50 mg120N/A

Frequently Asked Questions

Which brand of apigenin is considered the best?

The “best” brand depends on your priority. For verified manufacturing quality and a simple, trusted formula, Double Wood Supplements is an excellent choice due to its NSF certification. For high-purity athletes, Momentous holds NSF Certified for Sport. If your main goal is a very high single-ingredient dose, Nootropics Depot offers 200mg per capsule.

Does apigenin actually work?

Research suggests apigenin can bind to GABA receptors in the brain, supporting relaxation and a calm state conducive to sleep. Many users report improved sleep quality and reduced nighttime anxiety. However, as with any supplement, individual results vary, and it’s not a pharmaceutical sedative. Its effects are often described as a gentle, natural wind-down.

What is the best source of apigenin?

Apigenin is found naturally in chamomile tea, parsley, and celery. For a concentrated, dose-controlled supplement, capsules are the most reliable source. Supplements derived from chamomile extract are common. The best source for you is a supplement that provides a precise dose with transparency about its origin and purity.

Can I take apigenin every night?

Yes, apigenin is generally considered safe for nightly use, and many people incorporate it into a consistent bedtime routine. It does not appear to cause tolerance or dependence like some pharmaceutical sleep aids. As always, consult with your healthcare provider before starting any new supplement regimen, especially if you are pregnant, breastfeeding, or on medication.

Should I take apigenin with other supplements?

Apigenin is often paired with other calming nutrients like magnesium or L-theanine for a synergistic effect. Some research explores its interaction with other flavonoids like quercetin. It can be part of a broader stack, but starting with apigenin alone allows you to gauge its individual impact on your sleep and relaxation.

The Bottom Line

For most people starting an apigenin protocol, Double Wood Supplements Apigenin Capsules is the best overall choice. It provides a sensible 50mg dose from an NSF-certified facility, offering peace of mind about quality in a two-month supply.

If your budget allows for a premium brand with sport-level certification, choose Momentous Apigenin Supplement Capsules. If you’re seeking the highest single-capsule dose for a potent effect, go with Nootropics Depot Apigenin Capsules.

Ultimately, the most important factor is selecting a supplement with verifiable quality controls that fits your desired dose and formulation preferences, so you can confidently add it to your wellness routine.