10 Best Vitamins To Gain Weight in 2026
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The best weight gain supplement for most people is the Optimum Nutrition Serious Mass Gainer, which provides a substantial, nutrient-dense calorie surplus. For an extreme calorie formula, the Dymatize Super Mass Gainer excels, while Ensure Plus Nutrition Shake offers a clinically proven, convenient option. Gaining weight requires a consistent calorie surplus, which can be challenging to achieve through food alone, especially for athletes or those with fast metabolisms.
We researched specifications and user feedback to identify the best vitamins and supplements for weight gain, focusing on calorie content, nutritional profile, and practical use.
Top 10 Vitamins To Gain Weight in the Market
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The Best Vitamins To Gain Weight, Reviewed
Optimum Nutrition Serious Mass Gainer
What We Like
- Extremely high-calorie formula for bulking
- Substantial protein and carbohydrate content
- Includes over 20 essential vitamins and minerals
- Customizable with calorie-dense ingredients
Trade-offs
- Massive 2-scoop serving requires significant volume
- Primary mixing method is a shake, not a simple drink
A two-scoop serving delivers over 1,200 calories, which is the core appeal for those who find it hard to eat enough to gain weight. This product suits individuals in dedicated bulking phases who need a reliable, high-energy shake to consistently hit a surplus. It’s supported by 50 grams of protein for muscle support and an array of added vitamins for nutritional balance. The brand’s established reputation in sports nutrition adds a layer of expected quality control.
The trade-off is in the sheer scale of consumption; you are committing to a substantial shake, not a quick sip. This makes it less suitable for casual or light supplementation. For a more straightforward, ready-to-drink option focused purely on nutritional supplementation with fewer total calories, a product like Ensure Plus Nutrition Shake represents a different, more convenient approach to weight gain.
Dymatize Super Mass Gainer
What We Like
- Extremely high 1,280-calorie serving for mass gain
- 52g protein from a fast and slow-digesting blend
- Includes 1g creatine and 14 vitamins and minerals
- Calorie-dense formula simplifies meeting high energy needs
Trade-offs
- Large 245g carb serving may be excessive for some diets
- Only 8 servings per container, requiring frequent repurchase
The 1,280 calories packed into a single serving mean you can skip constant meal prep and still hit a serious caloric surplus. This makes it a straightforward choice for those whose diet alone falls short, especially when paired with intense training. Its blend of whey and casein protein aims to provide both immediate and sustained muscle support. The added creatine and micronutrients round out a formula designed for aggressive weight and muscle gain.
The main consideration is sheer volume. At 245 grams of carbs per shake, this is a commitment that might not suit someone with a sensitive stomach or a slower metabolism. Compared to something like the Transparent Labs Mass Gainer, which lists a lower carb count, the Dymatize formula is unapologetically focused on maximum caloric density above all else. It’s a tool for a specific, energy-intensive job.
Product photos

Ensure Plus Nutrition Shake
What We Like
- Clinically proven to help gain weight
- Includes immune-supporting zinc and vitamins
- Convenient, pre-mixed liquid format
- #1 doctor-recommended nutritional drink brand
Trade-offs
- Pre-mixed format limits portion customization
- 350 calories per shake, less than dedicated mass gainers
The 350 clinically proven calories make this a reliable tool for steady, measured weight gain. It’s suited for someone who needs a simple, trustworthy boost from a meal replacement, not a massive caloric surplus. The inclusion of 27 vitamins and minerals, plus immune support nutrients, means it addresses overall health, which is a smart priority for anyone rebuilding their body. This is the pick for when you want the reassurance of medical-grade nutrition without the guesswork.
This product’s role defines it. It’s a nutrition shake, not a hyper-caloric bomb. That makes it ideal for supplementing meals or replacing missed ones, but it won’t single-handedly fuel a bulking phase for a hard-training athlete. You’re choosing clinical credibility and convenience over raw, high-volume calorie loading.
Transparent Labs Mass Gainer
What We Like
- Clean formula with no artificial fillers
- Clinically dosed creatine for performance
- Slow-digesting carbs from whole food sources
- Complete amino acid profile from grass-fed whey
Trade-offs
- 770 calories per serving
- Weighs 7.1 pounds total
With 770 calories per serving from oat flour, sweet potato, and organic tapioca maltodextrin, this mass gainer uses whole-food sources for its bulk. The formula contains no artificial sweeteners, colors, or preservatives and is third-party tested, offering a straightforward choice for those prioritizing ingredient transparency in a caloric surplus plan.
Each serving delivers 770 calories, which is less than the 1280 calories in a serving of Dymatize Super Mass Gainer. For users targeting a very high daily calorie target, this difference means more servings or additional meals are needed to reach the same total intake.
Rule 1 Proteins Mass Gainer
What We Like
- Extremely high 1,220+ calorie formula for mass
- 6:1 carb-to-protein ratio prioritizes calorie surplus
- Made in GMP-certified US facilities
- Includes creatine monohydrate for muscle support
Trade-offs
- Two-scoop serving creates a very dense shake
- Formula relies heavily on carbohydrates over protein
With over 1,220 calories and a deliberate 6:1 carb-to-protein ratio, this mass gainer is engineered for one thing: a significant calorie surplus. It’s built for the individual who struggles to eat enough whole food to gain weight, providing a concentrated source of energy primarily from carbohydrates. The inclusion of creatine monohydrate and a clean manufacturing claim adds practical value for those focused on intense training and lean ingredient sourcing.
This mass gainer’s 6:1 carb-to-protein ratio focuses on calorie delivery for weight gain, so it’s suited for adding bulk rather than a high-protein diet. Compared to the Transparent Labs Mass Gainer, which lists 53g of protein and 110g of carbs per serving, Rule 1 provides a different macro balance. The formula is designed for efficient calorie addition when combined with a high-calorie diet and exercise, as directed.
Product photos

MuscleTech High Protein Mass Gainer
What We Like
- Extremely high 1,500-calorie serving
- Includes 60g of protein per serving
- Packs 304g of easily digestible carbs
- Contains HPLC-tested creatine monohydrate
Trade-offs
- Requires a six-scoop serving size
- Must be mixed with milk for full nutrient profile
A single serving delivers 1,500 calories, a decisive advantage for people with extremely high caloric needs who find whole-food meals insufficient. This product is built for significant weight gain. The inclusion of HPLC-tested creatine monohydrate and a substantial 60 grams of protein per serving directly supports the muscle-building component, aligning with a protocol focused on mass and strength.
Preparing a serving requires blending six scoops with two cups of skim milk, resulting in a very large shake. This high-volume approach delivers substantial fuel, as the mixed drink provides 1,500 calories and 60 grams of protein. It’s a straightforward formula designed for significant mass gain, prioritizing sheer nutritional quantity over a concentrated or minimalist mix.
Product photos

Kate Farms Organic Nutrition Shake
What We Like
- USDA Organic and Non-GMO Project Verified certification.
- Contains 27 vitamins and minerals.
- Free from common allergens and gluten.
- Pre-mixed, ready-to-drink convenience.
Trade-offs
- At 455 calories, it's lower in calories than most mass gainer powders.
- Contains only 20g of protein per serving.
- Pre-mixed format limits portion size customization.
Kate Farms provides 455 calories and 20 grams of protein in a certified USDA Organic, pre-mixed shake, making it a straightforward choice for clean, convenient supplementation. It includes 27 vitamins and minerals and phytonutrients from sources like organic turmeric and acai, which aligns with a preference for whole-food-derived nutrients. The formula is also Non-GMO Project Verified, Kosher, gluten-free, and made without common allergens.
Its calorie and protein levels are lower than those of dedicated mass gainers, such as the Dymatize Super Mass Gainer which provides 1280 calories. For someone with high calorie needs for weight gain, this shake serves more as a nutritional supplement than a primary high-calorie tool. It is available in flavors like vanilla, chocolate, and strawberry, and is made without artificial flavors or sweeteners.
Mutant Mass Extreme Gainer
What We Like
- Extremely high 1,270-calorie serving for surplus
- Multi-source protein blend for muscle support
- Clean, food-based carbohydrate sources for sustained energy
- Includes BCAAs and glutamine for recovery
Trade-offs
- At 1,270 calories, it is a very dense nutritional load per shake
- Vanilla is the only flavor option specified
A 1,270-calorie serving is the core fact here, making it a tool for those who genuinely struggle to eat enough. This product is built for the hard gainer who needs a massive, convenient calorie bomb to push past a plateau, not someone looking for a modest top-up. The protein blend and inclusion of recovery-focused aminos like glutamine frame it as a muscle-building aid, while the carbohydrate mix from barley and sweet potato suggests a focus on slower-digesting energy over simple sugars.
Mutant Mass Extreme Gainer delivers 1,270 calories per serving, so it is formulated specifically for individuals needing to significantly increase their daily calorie intake for weight gain. This makes it a substantial meal replacement, which could be excessive for someone with a more moderate appetite. The product is a specialized tool for addressing a specific dietary need rather than a casual supplement.
Product photos

BSN True-Mass Weight Gainer
What We Like
- 690 calories supports extreme training mass goals
- 2:1 carb-to-protein ratio for balanced macro delivery
- Blend of seven premium protein sources for sustained release
- Includes MCT fats for rounded nutritional value
Trade-offs
- 690 calories is modest next to Rule 1's 1,220+ calories
A 690-calorie serving with a deliberate 2:1 ratio of carbs to protein provides a balanced foundation for mass gain. This avoids the extreme carb load of some formulas, making it a suitable choice for someone seeking substantial caloric support without the digestive burden of a purely carb-centric shake. That effect is paired with its blend of seven protein sources for a sustained amino acid release.
With 690 calories per serving, BSN True-Mass provides substantial extra nutrition for building mass, positioning it as a formula for steady, manageable weight gain rather than the highest-calorie option. For those prioritizing sheer caloric density, this amount is conservative next to alternatives like the Rule 1 Proteins Mass Gainer and its 1,220+ calories. The product’s weight of 5.8 pounds results in a large container that requires significant storage space.
Product photos

Naturade Weight Gain Drink Mix
What We Like
- Balanced formula for healthy weight support
- Designed for active, demanding lifestyles
- Gentle support for appetite changes or fast metabolisms
- Flexible for use between meals or in smoothies
Trade-offs
- 1.3-pound container is smaller than most mass gainers
- Formula is not for extreme bulking
A calorie-dense nutrition drink mix positions this as a tool for healthy weight maintenance, not aggressive gain. It suits someone with an active routine or a fast metabolism who struggles to meet daily calorie needs through food alone, offering a gentle, nourishing boost without pressure. The blend of carbs, protein, vitamins, and minerals is designed for flexible, everyday use, whether blended into a smoothie or taken between meals.
Its most notable feature is the scale. At 1.3 pounds per container, this is a notably smaller commitment than something like the Optimum Nutrition Serious Mass Gainer. That makes it a prudent first test or a maintenance tool for someone who doesn’t want a gigantic tub of powder sitting around. It’s from a brand with nearly a century of history, which suggests a focus on balanced nutrition over sheer bulk.
Product photos

How We Evaluated Vitamins To Gain Weight
Our evaluation was based on researching product specifications, manufacturer data, and patterns in user feedback. We prioritized total calorie count per serving, the balance of protein and carbohydrates, and the inclusion of essential vitamins and minerals that support overall health and appetite. We also considered practical factors like serving size, mixability, and formula purity.
This guide compares the key specifications and features of each product to help you identify the best match for your nutritional goals.
For a deeper dive into these types of products, explore our dedicated guide on weight gain supplements.
What To Look For In Vitamins To Gain Weight
Choosing the right supplement depends on your specific weight gain goals, dietary needs, and lifestyle. A higher-calorie formula is not inherently better if it doesn’t align with your tolerance or nutritional targets.
Focus on calories per serving, protein and carb sources, and added nutrients. Consider serving size and mixability for daily use. Always check with a healthcare provider before starting any new supplement regimen.
Calorie Content
The primary function of a weight gain supplement is to provide a significant calorie surplus. Products range from around 350 calories per serving in some ready-to-drink shakes to over 1,500 calories in dedicated mass gainers. A higher calorie count is crucial for “hardgainers” with fast metabolisms, but it may be excessive for someone seeking gentle, balanced weight support. The serving size required to reach those calories also matters; a six-scoop serving can be difficult to consume compared to a two-scoop or pre-mixed option.
Macronutrient Profile
Look at the source and ratio of protein and carbohydrates. Protein is essential for muscle repair and growth, with whey protein being a common, high-quality source. Carbohydrates provide the energy surplus needed for weight gain and to fuel workouts.
Some formulas use a very high carb-to-protein ratio, like 6:1, which is designed for maximum caloric intake. Others offer a more balanced 2:1 ratio, which may support leaner mass gains. For those focused on building muscle, the quality of the protein is a key factor.
You can learn more about the role of specific vitamins in this process by reading about vitamins for muscle building.
Added Vitamins, Minerals & Ingredients
Many mass gainers include a broad spectrum of vitamins and minerals to fill nutritional gaps, which is especially helpful if your overall diet is lacking. Look for formulas that include B vitamins, zinc, and iron, as deficiencies in these can affect appetite and energy levels.
Performance ingredients like creatine monohydrate are common in formulas aimed at athletes, as they can support strength and muscle volume. For those with dietary preferences or sensitivities, check for certifications like USDA Organic or labels indicating a formula is free from artificial fillers and common allergens.
If you’re also engaging in regular training, consider how a comprehensive multivitamin for weightlifting could complement your regimen.
- Check the serving size: Ensure you can realistically consume the required volume, whether it’s two scoops or six.
- Review carbohydrate sources: Look for complex carbs from oats or sweet potato for sustained energy versus simple sugars.
- Consider mixability: Some powders blend easily with water, while others may require a blender for a smooth shake.
- Assess your goals: Determine if you need maximum calories for bulking or a balanced formula for healthy weight support.
- Consult a professional: This is especially important when considering vitamins for kids or if you have underlying health conditions.
The best supplement is the one you can consistently incorporate into your daily routine to meet your calorie targets.
Vitamins To Gain Weight Compared
The comparison table below highlights key specifications like calories, protein, and serving size to help you see the differences at a glance.
| Product | Calories per serving | Protein per serving | Form |
|---|---|---|---|
| Optimum Nutrition Serious Mass Gainer | Over 1,200 | 50g blended protein | Powder |
| Dymatize Super Mass Gainer | 1,280 | 52g | Powder |
| Ensure Plus Nutrition Shake | 350 calories | 16g protein | Ready-to-drink shake |
| Transparent Labs Mass Gainer | 770 | 53g grass-fed whey | Powder |
| Rule 1 Proteins Mass Gainer | Over 1,220 | 40g all-whey protein | Powder |
| MuscleTech High Protein Mass Gainer | 1,500 | 60g | Powder |
| Kate Farms Organic Nutrition Shake | 455 | 20g | Pre-mixed shake |
| Mutant Mass Extreme Gainer | 1,270 | 46 g | Powder |
| BSN True-Mass Weight Gainer | 690 | 50g | Powder |
| Naturade Weight Gain Drink Mix | N/A | N/A | Drink mix |
Frequently Asked Questions
What is the best vitamin supplement to gain weight?
There isn’t a single “best” vitamin; effective weight gain requires a calorie surplus, often from a combination of macronutrients and micronutrients. High-calorie mass gainer powders like our Best Overall pick, Optimum Nutrition Serious Mass Gainer, are designed specifically for this purpose, packing calories, protein, carbs, and essential vitamins into a single serving.
What helps gain weight fast?
Creating a consistent calorie surplus is the fastest path to weight gain. This involves consuming more calories than you burn, often aided by calorie-dense shakes or protein supplements. Combining this with strength training helps ensure the gained weight includes muscle mass, while ensuring adequate sleep and managing stress supports overall metabolism and recovery.
Can Lamictal cause weight gain?
Lamictal (lamotrigine) is not typically associated with significant weight gain; in fact, weight loss is a more commonly reported side effect. Any concerns about medication effects on weight or appetite should be discussed directly with your prescribing healthcare provider, as individual reactions can vary.
What are the best supplements for gaining weight?
The best supplements are those that efficiently help you achieve a calorie surplus. These include high-calorie mass gainers, protein powders to increase daily protein intake, and certain vitamins like B-complex or zinc if a deficiency is suppressing your appetite. Learn more about gaining weight with vitamins. The choice depends on your total caloric needs and dietary preferences.
Are weight gain pills effective?
Some weight gain pills or appetite stimulants can be effective, particularly when a medical condition suppresses appetite. However, for most healthy individuals seeking to gain mass, calorie-dense powders and shakes are generally more effective because they deliver substantial macronutrients (protein, carbs) alongside calories, rather than just stimulating hunger.
The Bottom Line
For athletes and serious lifters aiming to bulk up, the Optimum Nutrition Serious Mass Gainer is the most effective tool, delivering a high-calorie, nutrient-packed shake. If your budget is tight or you need a doctor-trusted option for general weight support, look to the Best Clinically Proven pick, Ensure Plus.
For those prioritizing clean ingredients or an organic formula, the Transparent Labs and Kate Farms shakes are excellent choices. Ultimately, the most important factor is finding a product with a calorie count and serving size you can consistently use to maintain the surplus needed to reach your goals.




