10 Best Dgl Licorice Supplements in 2026

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Our research points to Natural Factors DGL Chewable Licorice Root Extract as the best overall DGL supplement, offering a high tablet count and allergen-free formula for daily maintenance. The Best Chewable Formula is Nature’s Way DGL Chewable Tablets, while Best Powder Format goes to Vital Nutrients DGL Powder for adjustable dosing.

Finding a reliable DGL supplement means navigating varying potencies, formats, and ingredient quality. Many products are marketed as “deglycyrrhizinated,” but independent testing has found some contain more of the problematic compound than expected. This guide is based on research into manufacturer specifications, expert analysis, and patterns in consumer feedback to help you identify trustworthy options that fit your routine.

Top 10 DGL Licorice Supplements in the Market

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The Best DGL Licorice Supplements, Reviewed

#1Best Overall

Natural Factors DGL Chewable Licorice Root Extract

Natural Factors DGL Chewable Licorice Root Extract
Tablet Count180 tablets
FormChewable tablet
Key IngredientDGL licorice root extract
Dietary ProfileVegan, non-GMO
Dimensions3.1" L x 3.1" W x 4.8" H
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What We Like

  • High tablet count per bottle for extended use
  • Chewable form for convenient pre-meal routine
  • Comprehensive vegan and allergen-free formula
  • Family-owned brand with full manufacturing control

Trade-offs

  • Requires chewing 1-3 tablets before meals

With 180 chewable tablets, this bottle lasts through a long-term digestive support protocol without frequent reordering. The straightforward DGL formula, free from common allergens and artificial additives, suits anyone needing a gentle, predictable aid for stomach lining integrity, especially those with multiple dietary restrictions. It’s the workhorse pick for consistent, uncomplicated use.

Natural Factors offers a straightforward DGL formula focused on supporting digestion and stomach lining integrity, without additional herbal blends found in some other supplements. Its chewable tablets are taken before meals as part of a simple routine. The family-owned brand maintains direct control over manufacturing, which can appeal to buyers seeking a transparent, vegan product free from many common allergens and artificial additives.

Best for: Individuals seeking a long-lasting supply of a pure, allergen-free DGL supplement for daily digestive maintenance. Not ideal for those wanting a multi-herb blend or a powder form for precise dosing.

Product photos

#2Best Chewable Formula

Nature's Way DGL Chewable Tablets

Nature's Way DGL Chewable Tablets
Servings per container33
Tablets per serving3
Tablet formChewable
Key ingredientGutGard DGL
Allergen/dietary notesVegan, gluten-free, dairy-free
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What We Like

  • Convenient, licorice-flavored chewable tablets.
  • Features clinically studied GutGard DGL extract.
  • Broadly allergen-friendly and vegan formulation.
  • Moderate 100-count container size.

Trade-offs

  • Requires six tablets daily for full dose.
  • 33 servings per bottle is a mid-range supply.

The requirement to chew three tablets twice daily defines this formula. It’s a straightforward protocol for someone who prefers a chewable over capsules or powder and wants a specific, clinically referenced DGL extract. The product suits a disciplined user comfortable with a higher tablet count per serving, and its vegan, allergen-free profile removes common barriers to trial. This is a focused choice for targeted digestive comfort, not a comprehensive blend.

The daily regimen requires a commitment of six chewable tablets, taken after meals in the morning and evening. This places it between other formats, as it involves more tablets than a single-capsule option like Pure Encapsulations DGL Plus but provides more servings than a basic trial. The 100-count bottle offers 33 total servings, which is fewer than the 180-tablet offering from Natural Factors.

Best for: The buyer seeking a straightforward, chewable DGL supplement with a clinically referenced extract and no common allergens. Not ideal for those who want maximum servings per bottle or prefer a single-capsule daily dose.

Product photos

#3Best Powder Format

Vital Nutrients DGL Powder

Vital Nutrients DGL Powder
FormatPowder
Net weight120g
Allergen profileGluten, dairy, soy free
Quality verificationThird-party lab tested
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What We Like

  • Powder format allows for precise, adjustable dosing
  • Glycyrrhizin removed to avoid common side effects
  • Clean, hypoallergenic, vegan formula without fillers
  • Trusted by healthcare practitioners for 30 years

Trade-offs

  • Powder requires mixing, unlike a chewable tablet
  • No built-in flavoring to mask the herbal taste

The powder format is the single biggest practical advantage here, letting you dial in the exact dose you need or mix it into a smoothie without chewing through another tablet. It suits anyone who wants control over their serving size or finds chewables inconvenient. The rigorous processing to keep glycyrrhizin below 0.6% makes it a safer bet for long-term use, and the clean, vegan formula from a practitioner-founded brand adds a layer of trust that’s hard to quantify.

Unlike chewable tablets like Natural Factors DGL Chewable, this product comes as a powder that requires measuring and mixing before use. For some users, this preparation is a minor ritual, but for others seeking quick relief, it can be a significant inconvenience.

Best for: The tinkerer who prefers precise, adjustable dosing and doesn't mind mixing a powder. Not ideal for someone seeking grab-and-go convenience or who dislikes the natural taste of herbs.
#4Best Standardized Extract

Designs for Health DGL Root Chewables

Designs for Health DGL Root Chewables
FormChewable tablets
Standardized FormYes
Glycyrrhizin ContentVery low
Dietary FeaturesGluten-Free, Vegetarian-friendly
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What We Like

  • Standardized, high-quality DGL extract
  • Very low glycyrrhizin minimizes side effect risk
  • Pleasant-tasting, sugar-free chewable format

Trade-offs

  • 90-count bottle offers fewer servings than some 180-count rivals
  • No explicit fructose-free claim like some competitors

Designs for Health uses a standardized, high-quality form of DGL, so each chewable delivers a consistent dose. This formula works without some of the potential side effects of prolonged high-dose full-spectrum licorice, including hypertension and fluid retention, which suits users seeking targeted gastric mucosa support. It fits buyers who prioritize the brand’s practitioner-grade, no-compromise approach to ingredients in a pleasant-tasting, sugar-free tablet.

The product comes in a 90-tablet supply, which is a lower count than options like the 180-tablet Natural Factors DGL Chewable. This means for a consistent daily regimen, you would need to reorder this bottle more frequently than some competing products. The focus is on the brand’s clinically-trusted reputation and strict quality standards rather than on providing the highest tablet quantity.

Best for: The buyer seeking a no-compromise, standardized DGL extract from a clinically trusted brand for consistent digestive support. Not ideal for those prioritizing the largest bottle size per purchase.

Product photos

#5Best For Digestive Comfort

Integrative Therapeutics Rhizinate Digestive Support

Integrative Therapeutics Rhizinate Digestive Support
FormatChewable tablets
Count100 tablets
GlycyrrhizinLess than 1%
Key ExclusionsNo wheat, gluten, soy, dairy
Dimensions4.5"L x 2.7"W x 2.6"H
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What We Like

  • Chewable formula for convenient use
  • Contains less than 1% glycyrrhizin
  • Free from major common allergens
  • Backed by 25+ year brand history

Trade-offs

  • At 0.4 lbs, it's heavier than the 0.3 lb Nature's Way bottle
  • Only 100 count versus some 180-count competitors
  • Lacks added botanicals like slippery elm or marshmallow

Rhizinate Digestive Support comes as a chewable tablet, so you can take it discreetly anywhere without needing water. Its formula contains less than 1% glycyrrhizin, as stated on the label, and is free from wheat, gluten, soy, dairy, artificial colors, or preservatives. This makes it a straightforward choice for someone who wants a simple, clean DGL supplement focused solely on providing digestive comfort through supporting the stomach’s protective factors.

The product is a single-ingredient DGL supplement. Integrative Therapeutics, the brand behind it, notes a 25-year history where patients and clinicians have trusted its dedication to quality, potency, and accuracy. Its value lies in this purity and the brand’s stated transparency about sourcing and manufacturing.

Best for: Someone seeking a simple, chewable DGL from a trusted brand for targeted digestive soothing.
#6Best Professional Strength

Planetary Herbals DGL Chewable Tablets

Planetary Herbals DGL Chewable Tablets
Tablet Count100 Chewable Tablets
Suggested UseChew 1 tablet before each meal
ManufacturingMade in USA under cGMPs
Key IngredientDeglycyrrhizinated Licorice Root Extract
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What We Like

  • Professional strength DGL formulation
  • Convenient chewable tablet format
  • Manufactured under strict FDA cGMPs
  • Made in the USA

Trade-offs

  • Lower tablet count than Natural Factors' 180-count option
  • Contains 100 tablets, a lower count than Natural Factors' 180-tablet option.

Planetary Herbals DGL Chewable Tablets carry a ‘Professional Strength’ designation, indicating a concentrated extract aimed at targeted support for the stomach lining. The suggested use is to chew one tablet before each meal, integrating the supplement directly into a meal-based routine. It is manufactured in Scotts Valley, CA, under FDA cGMPs, which are established standards for production quality control.

The product is presented in a chewable tablet format, which provides a pre-measured dose without the need for measuring tools required by a powder. Its dimensions are 2.4 by 2.4 by 4.3 inches with a weight of 0.3 pounds, giving it a compact profile similar to the Nature’s Way DGL bottle. This size makes it easy to store in a medicine cabinet or carry in a bag.

Best for: A user following a pre-meal supplement routine who prefers a chewable, professionally-strength DGL made in a cGMP facility.

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#7Best Herbal Combination

Pure Encapsulations DGL Plus Capsules

Pure Encapsulations DGL Plus Capsules
FormCapsules
Herbal BlendDGL, aloe vera, marshmallow root, slippery elm
Allergen StatusFree from common allergens, gluten, GMOs
Quantity60 capsules
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What We Like

  • Combines DGL with three complementary herbs
  • Vegan and free from common allergens
  • Herbal blend with aloe and marshmallow

Trade-offs

  • 60-capsule supply
  • Capsule format only

Its formula combines deglycyrrhizinated licorice with aloe vera, marshmallow root, and slippery elm bark, providing a multi-herb approach to gastrointestinal support in one capsule. The product is made with vegan ingredients and is free from gluten and common allergens, fitting for someone with dietary restrictions. Pure Encapsulations DGL Plus was included in a ConsumerLab review of licorice and DGL supplements.

The trade-off is in the serving count and form. With 60 capsules, it’s a shorter supply than some bulk chewable options like Natural Factors DGL Chewable, which offers 180 tablets. The capsule format also means you miss the potential localized soothing effect of chewing a tablet or mixing a powder like Vital Nutrients DGL Powder, which some find more directly comforting. Your choice hinges on whether you prioritize a blended, convenient capsule or a higher-volume, more direct delivery method.

Best for: The buyer who wants a well-rounded, allergen-conscious herbal blend in a convenient capsule for comprehensive gut health support. Not ideal for someone seeking a high-volume, chewable tablet or a pure DGL powder for more direct, dose-specific use.

Product photos

#8Best Multi-Herb Support

Thorne GI Relief DGL Blend

Thorne GI Relief DGL Blend
Key IngredientsDGL, slippery elm, marshmallow, aloe
Format180 capsules
Third-Party CertificationNSF Contents Certified
Alternative UseCan mix capsule contents into tea
Brand Trust#1 recommended clinical brand (2026 survey)
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What We Like

  • Multi-herb blend for comprehensive GI support
  • NSF third-party certification for ingredient integrity
  • Versatile capsule-to-tea format for upper tract relief
  • Highly trusted brand among practitioners

Trade-offs

  • Capsule format requires extra step for tea preparation
  • Lacks the convenience of pre-formulated chewable tablets

The inclusion of four distinct mucilaginous botanicals. DGL, slippery elm, marshmallow root, and aloe vera, means this isn’t just a single-ingredient fix but a broad-spectrum formula designed to soothe irritation throughout the entire gastrointestinal tract. It suits someone seeking a clinical-grade, multi-herb approach who values third-party verification and a brand consistently recommended by healthcare professionals. The ability to open the capsule and mix the powder into a warm tea directly targets esophageal discomfort, a specific benefit not all formats offer.

The capsule format requires an extra step if you prefer the tea preparation method described for irritated mucous membranes. Someone valuing pure convenience might find a pre-made chewable tablet simpler for immediate use. This blend offers a versatile format with four botanical ingredients, and its contents are third-party certified to match the label.

Best for: The buyer seeking a premium, multi-herb digestive support formula with third-party certification and flexible administration. Not ideal for those who strictly want the simplest, ready-to-take chewable format.

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#9Best High Potency

Nutricost DGL Extract Capsules

Nutricost DGL Extract Capsules
Serving Size1 capsule
DGL Extract per Serving500mg (10:1 extract)
Servings per Bottle120
Third-Party TestingISO-accredited labs
Manufacturing StandardNSF Certified GMP facility
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What We Like

  • High 500mg dose of concentrated 10:1 extract
  • Substantial 120-serving supply per bottle
  • Rigorous third-party testing for purity
  • Manufactured in a certified, compliant facility

Trade-offs

  • Capsule form may be less convenient than chewables for some
  • Single-ingredient formula lacks supporting herbs found in blends

A 500mg serving of a 10:1 extract delivers a concentrated, high-potency dose in every capsule, making it a straightforward choice for someone focused purely on a strong, singular DGL impact. The 120-count bottle supports a consistent daily protocol without frequent reordering, and the manufacturing and testing credentials provide a level of transparency that appeals to a skeptical buyer who prioritizes verified content over marketing claims. This is for the person who wants the active component, measured precisely and delivered without frills.

The Nutricost DGL Extract provides 500mg of a 10:1 concentrate per capsule, offering a potent dose in a simple format. Unlike products such as Thorne GI Relief, which combines multiple herbs, this is a single-ingredient supplement. For those seeking a straightforward, high-strength source of deglycyrrhizinated licorice extract from a brand emphasizing third-party testing, it fits the bill; individuals preferring a multi-herb formula would need to choose a different product.

Best for: The supplement user seeking a high-potency, singular-ingredient DGL extract from a transparently tested source. Not ideal for those who prefer the convenience of chewable tablets or a multi-herb digestive blend.

Product photos

#10Best Fructose-Free Option

Integrative Therapeutics Rhizinate Fructose Free

Integrative Therapeutics Rhizinate Fructose Free
FormChewable tablets
Count100 tablets
Glycyrrhizin contentLess than 1%
Free fromSugar, gluten, soy, dairy
Dimensions2.4" x 2.4" x 4.3"
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What We Like

  • Fructose-free chewable formula
  • Contains less than 1% glycyrrhizin
  • Gluten, soy, and dairy free
  • Compact, lightweight bottle

Trade-offs

  • Chewable form limits dosing flexibility versus powders

The fructose-free formula is the decisive feature here, making it a clear choice for anyone sensitive to common sweeteners or following a strict FODMAP protocol. It delivers the core DGL benefit, supporting protective factors in the digestive tract, without that particular irritant. The chewable form and a clean label free from major allergens align it with a minimalist, targeted approach to digestive comfort support.

The trade-off is in the serving count. With 100 tablets, the bottle is notably more compact and lighter than, say, the Natural Factors DGL Chewable, but you’ll be refilling it more often if this becomes a daily protocol. It’s a focused tool for a specific need, not a bulk stock-up option. For someone who values purity of ingredients over sheer volume, this spec sheet reads correctly.

Best for: Individuals seeking a DGL supplement with a strict fructose-free and allergen-minimized formula. Not ideal for those who prefer powder forms for adjustable dosing or want the largest bottle count per purchase.

Product photos

How We Evaluated DGL Supplements

The assessment of products was based on available manufacturer information and common quality indicators. Priority was given to formulas that specify a low or verified glycyrrhizin content, as this compound is removed to minimize potential side effects. Other considerations included the convenience of the format, such as chewable tablets versus powders or capsules, and whether complementary herbs were included for broader digestive support.

Our research into the best DGL products also considered supply size and allergen profiles. It’s important to note that this is a research-based assessment; we did not conduct chemical testing ourselves but relied on published data and consumer reports to identify consistent strengths and trade-offs.

What To Look For In DGL Licorice Supplements

Choosing a DGL supplement involves more than just picking a brand. You need to verify its formulation for safety, decide on the most practical format for your habits, and consider whether you want targeted support or a broader herbal blend.

Look for products that specify a low glycyrrhizin percentage, choose between convenient chewables or adjustable powders, and decide if a single-ingredient or multi-herb formula best suits your digestive needs.

Glycyrrhizin Content & Verification

The primary purpose of DGL is to provide the benefits of licorice without its glycyrrhizin, which in high amounts can affect blood pressure and electrolyte balance. Research indicates significant variation, with some products failing testing because they contained higher-than-expected levels. Look for products that explicitly state a low glycyrrhizin percentage, often “less than 1%” or “0.5%,” and preferably those with third-party verification. This is a critical safety checkpoint before considering any other feature.

Format & Dosing Convenience

DGL comes in chewable tablets, powders, and capsules, each with different advantages. Chewable tablets are popular for their convenience and are often taken before meals, as suggested for digestive support. Powders, like our Best Powder Format pick, allow for precise, adjustable dosing but require mixing. Capsules offer a simple swallow-and-go option but lack the pre-meal ritual of a chewable. Your choice should align with your daily routine and willingness to measure or mix.

Formula Focus & Additional Ingredients

Decide if you want a pure DGL extract or a blend with other supportive herbs. Single-ingredient formulas offer straightforward, potent DGL support and are ideal for those following a specific protocol. Blends often include herbs like slippery elm, marshmallow root, or aloe vera, which may provide complementary soothing for the digestive tract. If you’re exploring broader digestive support, you might also consider reading about acid reflux supplements or slippery elm supplements.

  • Check the serving size and number of tablets required per dose; some require multiple chewables.
  • Review the allergen statement if you have sensitivities to gluten, soy, dairy, or other common ingredients.
  • Consider the total servings per bottle to gauge value and how often you’ll need to reorder.

A trustworthy DGL product will transparently disclose its glycyrrhizin levels and manufacturing standards.

DGL Licorice Supplements Compared

The following table compares key details across our top picks to help you see the differences at a glance.

ProductFormTablet Count / Net WeightKey Ingredient / BlendDietary Profile
Natural Factors DGL Chewable Licorice Root ExtractChewable tablet180 tabletsDGL licorice root extractVegan, non-GMO
Nature's Way DGL Chewable TabletsChewable100 CountGutGard DGLVegan, gluten-free, dairy-free
Vital Nutrients DGL PowderPowder120gDGL Licorice Root ExtractGluten, dairy, soy free
Designs for Health DGL Root ChewablesChewable tablets90 TabletsDeglycyrrhizinated LicoriceGluten-Free, Vegetarian-friendly
Integrative Therapeutics Rhizinate Digestive SupportChewable tablets100 tabletsDeglycyrrhizinated Licorice (DGL)Vegan, Gluten-Free, Dairy-Free
Planetary Herbals DGL Chewable TabletsChewable Tablets100 Chewable TabletsDeglycyrrhizinated Licorice Root ExtractN/A
Pure Encapsulations DGL Plus CapsulesCapsules60 capsulesDGL, aloe vera, marshmallow root, slippery elmFree from common allergens, gluten, GMOs
Thorne GI Relief DGL BlendCapsules180 capsulesDGL, slippery elm, marshmallow, aloeN/A
Nutricost DGL Extract CapsulesCapsules120 CapsulesDGL Deglycyrrhizinated Licorice ExtractGluten-Free, Vegan, GMO Free
Integrative Therapeutics Rhizinate Fructose FreeChewable tablets100 tabletsDeglycyrrhizinated Licorice (DGL)Sugar, gluten, soy, dairy free

Frequently Asked Questions

Which DGL licorice supplement is the best?

Based on our research into formulation, supply, and user feedback, the Natural Factors DGL Chewable Licorice Root Extract is the best overall. It provides a high tablet count for extended use in a convenient, allergen-free chewable format, making it a solid choice for daily digestive maintenance.

Is it okay to take DGL every day?

Many DGL supplements are designed for daily, pre-meal use as part of a digestive support routine. However, duration guidelines vary. Some sources suggest DGL products may be safe for use for up to four months, but it’s always best to consult with a healthcare provider for personalized, long-term use advice.

How much DGL licorice should I take for GERD?

Dosage varies by product potency and format. Typical chewable tablet doses range from one to three tablets taken before meals, as indicated on the label. While some small studies suggest DGL may help with acid reflux symptoms, more research is needed. It’s crucial to follow the specific dosage instructions on your chosen supplement and discuss it with a doctor.

Who should not take deglycyrrhizinated licorice?

Individuals with certain health conditions, such as kidney disease, heart disease, or high blood pressure, should consult a doctor before use. Pregnant or breastfeeding individuals are generally advised to avoid licorice products. Always check with a healthcare professional, especially if you are on medications, to assess potential interactions.

What’s the difference between DGL and regular licorice supplements?

DGL (deglycyrrhizinated licorice) has had most or all of the glycyrrhizin compound removed to avoid its potential side effects. Regular licorice root supplements or candies contain glycyrrhizin, which can be harmful in large amounts. For safety and targeted digestive use, a verified DGL product is the appropriate choice.

The Bottom Line

For a reliable, long-lasting DGL supplement, Natural Factors DGL Chewable Licorice Root Extract is our top recommendation. It’s a good fit for those seeking a pure, allergen-free formula for daily use. If you’re on a budget or want a clinically studied extract, consider the Best Chewable Formula, Nature’s Way DGL Chewable Tablets. Those needing precise dosing should look at the Best Powder Format, Vital Nutrients DGL Powder.

Ultimately, the most critical factor is selecting a product that transparently verifies its low glycyrrhizin content, ensuring you get the intended benefits without unnecessary risk. Always pair your supplement choice with professional medical advice for your specific digestive health needs.