10 Best Dgl Supplements in 2026

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Our best overall pick is the Nature’s Way DGL Ultra Chewable Tablets for its reliable, standardized formula in a convenient, chocolate-flavored chewable. For a high-count bottle, consider Natural Factors DGL Chewable Tablets, while Planetary Herbals DGL Chewable Tablets offer professional-strength potency. Finding a DGL supplement that fits your daily routine and specific digestive concerns can be confusing.

You need to consider the format, potency, and whether the glycyrrhizin has been adequately removed. We researched specifications, manufacturer data, and patterns in expert and owner feedback to create this list of ten top choices.

Top 10 DGL Supplements in the Market

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The Best DGL Supplements, Reviewed

#1Best Overall

Nature's Way DGL Ultra Chewable Tablets

Nature's Way DGL Ultra Chewable Tablets
Servings per bottle90
DGL per serving75mg GutGard extract
FormChocolate chewable tablet
Dietary featuresVegan, gluten-free, dairy-free
Dosage1 tablet after food, twice daily
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What We Like

  • Uses GutGard, a standardized DGL extract
  • Convenient chocolate-flavored chewable format
  • Clean, allergen-conscious formulation
  • Sustainable 97% post-consumer recycled bottle

Trade-offs

  • Twice-daily, after-food regimen demands routine

The 75mg of GutGard extract per tablet provides a standardized, reliable dose of DGL, which is the main reason it stands out. For someone seeking predictable digestive support from a well-known brand, this offers a straightforward, no-surprises formula. The chocolate-flavored chewable makes it easy to take without water, fitting neatly into a daily routine. Its vegan and allergen-free profile also means fewer compatibility concerns, which is a relief for anyone scanning labels.

Nature’s Way DGL Ultra Chewable Tablets deliver a single, extra-strength 75mg serving of GutGard extract per tablet, which simplifies dosing for consistent digestive support. The formula is a chocolate-flavored chewable, making the daily routine more palatable than swallowing capsules. It’s also formulated without gluten, soy, dairy, or artificial additives, and the bottle uses recycled materials, aligning with clean-label preferences.

Best for: Someone seeking a reliable, easy-to-take daily DGL supplement from an established brand with a clean label. Not ideal for those prioritizing the absolute highest single-dose potency above all else.

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#2Best High-Count Bottle

Natural Factors DGL Chewable Tablets

Natural Factors DGL Chewable Tablets
Tablet Count180 chewable tablets
Key IngredientDeglycyrrhizinated licorice root extract
Dietary ProfileVegan, non-GMO, free from major allergens
Suggested Use1 tablet 1-3 times daily before meals
Bottle Dimensions3.1 x 3.1 x 4.8 inches
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What We Like

  • High 180-tablet count per bottle
  • Vegan and free from common allergens
  • Family-owned brand with full manufacturing control
  • Simple pre-meal chewable routine

Trade-offs

  • Bottle is taller than some competitors like Planetary Herbals
  • Requires chewing 20 minutes before multiple meals daily

A bottle of 180 chewable tablets stands out for anyone building a long-term digestive support routine. This high count means fewer reorders and reliable availability, which suits the skeptical tinkerer who wants to test a protocol consistently over weeks. The formula is deliberately clean, vegan and stripped of artificial additives and major allergens, which aligns with a preference for straightforward, evidence-based ingredients over marketing fluff. It’s a logical pick for someone methodically tracking how a gentle mucosal support supplement fits into their daily regimen.

Natural Factors DGL Chewable Tablets require taking one tablet up to three times daily before meals, a routine that integrates digestion support directly into a pre-meal schedule. The bottle stands 4.8 inches tall, which is taller than Planetary Herbals’ 4.3-inch container, so it may require more vertical shelf space. Its formula is free from artificial colors, preservatives, sweeteners, and common allergens like dairy, soy, and gluten, making it a straightforward vegan choice.

Best for: Methodical supplement users seeking a high-count, allergen-free DGL for consistent long-term testing. Not ideal for those wanting a compact bottle or a guaranteed flavor to mask the herbal taste.
#3Best Professional Strength

Planetary Herbals DGL Chewable Tablets

Planetary Herbals DGL Chewable Tablets
FormChewable tablet
Tablet count100 tablets
Manufacturing standardcGMP, FDA-established
Made inUSA (Scotts Valley, CA)
Suggested use1 tablet before each meal
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What We Like

  • Professional-strength DGL formulation.
  • Manufactured under strict cGMP standards.
  • Convenient chewable tablet form.
  • Made in a US facility.

Trade-offs

  • Only one suggested use protocol

The ‘Professional Strength’ label indicates this formula is intended for serious, regular use. With 100 tablets and instructions to chew one before each meal, it’s designed for a structured daily regimen. It suits someone seeking a straightforward, high-potency DGL supplement manufactured in the USA under established FDA Good Manufacturing Practices.

The trade-off is in flexibility. Compared to the smaller, lighter Integrative Therapeutics Rhizinate Fructose Free bottle, the Planetary Herbals container is taller and less pocket-friendly. This is a workhorse supplement for a dedicated routine, not necessarily for tossing in a day bag.

Best for: Someone committed to a pre-meal, professional-strength DGL protocol from a US manufacturer. Not ideal for those seeking a highly portable bottle or flexible, as-needed dosing instructions.

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#4Best Glycyrrhizin-Free Formula

Integrative Therapeutics Rhizinate Chewable Tablets

Integrative Therapeutics Rhizinate Chewable Tablets
Tablet Count100 Chewable Tablets
Glycyrrhizin ContentContains Less than 1%
Allergen-FreeVegan, Gluten-Free, Dairy-Free
Package Dimensions4.5 x 2.7 x 2.6 Inches
Product Weight0.4 Pounds
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What We Like

  • Specifically formulated with less than 1% glycyrrhizin.
  • Chewable tablet form for convenient, on-the-go use.
  • Free from common allergens like gluten, soy, and dairy.
  • Backed by a brand with over 25 years in the industry.

Trade-offs

  • The 0.4-pound package is bulkier than some 100-count competitors.
  • Chewable format may not suit those preferring capsules.
  • No specific DGL extract amount or potency is listed per serving.

Integrative Therapeutics Rhizinate is defined by its commitment to a glycyrrhizin-free formula, containing less than 1% of the compound. This makes it a prime candidate for anyone particularly cautious about the potential side effects associated with standard licorice root, seeking digestive comfort support with that specific safety margin. The chewable, allergen-free tablets and the brand’s long-standing transparency suit a methodical buyer who prioritizes purity claims over just potency numbers on a label.

Integrative Therapeutics Rhizinate uses a physical package that’s a bit larger than some others holding the same tablet count, like the more compact Planetary Herbals DGL bottle. You’re getting 100 servings in a box that demands a little more shelf space. For someone who has discussed glycyrrhizin sensitivity with a clinician, this is a logical, premium-tier option. Others just seeking a basic DGL might prefer a simpler chewable.

Best for: Individuals seeking a well-established brand's chewable DGL supplement for general digestive comfort, with a formulation low in common allergens. Not ideal for those requiring a completely glycyrrhizin-free product or a specific milligram-per-serving potency.
#5Best For Mucosal Lining

Swanson DGL Chewable Tablets

Swanson DGL Chewable Tablets
Dose per tablet385 milligrams
Tablet count180 chewables
Product formChewable tablet
Dietary compatibilityVegan, Vegetarian, Non-GMO
Shelf life guideline24 months from manufacture
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What We Like

  • High tablet count for extended use
  • Chewable form for convenience
  • Specifically supports mucosal lining health
  • Broad dietary compatibility

Trade-offs

  • Large 3.9-inch cube container for shelf storage.
  • Potency comparisons lack verified dosage data.

A 180-count bottle of 385mg chewable tablets positions this as a workhorse for a dedicated DGL regimen. The formulation is straightforward, targeting the stomach and intestinal mucosal lining with a dose meant for consistent, daily support rather than acute intervention. It suits someone focused on long-term gastrointestinal tissue maintenance who prefers the simplicity of an unflavored, chewable tablet and values a product free from common allergens and GMOs.

The Swanson DGL chewables come in a large, cube-shaped container that occupies noticeable shelf space. While the 385-milligram formulation provides daily support for mucosal lining health, its per-tablet potency is not directly comparable to other brands without verified dosage data. For users prioritizing a vegan, non-GMO supplement in a high-volume package, this product offers a straightforward choice.

Best for: The user prioritizing a long-term, daily protocol for mucosal lining support with a high-count, allergen-conscious supplement. Not ideal for someone seeking maximum portability or the highest per-tablet potency for occasional use.

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#6Best Sugar-Free Formula

Designs for Health DGL Root Chewables

Designs for Health DGL Root Chewables
Tablet Count90 Tablets
Key IngredientDeglycyrrhizinated Licorice Root
FormChewable
Additional ComponentsGlycine, Calcium Glycerophosphate
Dietary FeaturesGluten-Free, Vegetarian
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What We Like

  • Sugar-free, pleasant-tasting chewable formula
  • Standardized DGL with very low glycyrrhizin content
  • Includes glycine and calcium for synergistic support
  • Brand trusted by functional medicine professionals

Trade-offs

  • No flavor specified, unlike chocolate-flavored competitors
  • Count of 90 is mid-range, not the highest in the guide

This sugar-free formula offers a pleasant-tasting chewable option for those monitoring sugar intake. It uses a standardized DGL extract with very low glycyrrhizin content, which provides the recognized mucosal soothing effects while aiming to avoid potential side effects associated with full-spectrum licorice, such as hypertension. The formula also includes the amino acid glycine and calcium glycerophosphate, as part of the brand’s strict approach to quality raw material selection. Designs for Health is the practitioner supplement brand most recommended and personally trusted by functional medicine professionals.

Nature’s Way DGL Ultra has a distinct chocolate flavor, which can be helpful if you dislike the natural taste of licorice and want to ensure you’ll take it consistently. Its 90-tablet bottle is a moderate size, offering enough servings to see if this sugar-free formula suits you before buying a larger supply.

Best for: Buyers seeking a sugar-free DGL chewable from a practitioner-trusted brand. Not ideal for someone who strongly prefers a flavored chewable like chocolate.

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#7Best Gummy Format

Enzymedica DGL Stomach Soothe Gummies

Enzymedica DGL Stomach Soothe Gummies
FormatChocolate-flavored gummies
Dose per serving400 mg (10:1 extract)
Key ingredientDeglycyrrhizinated licorice (DGL)
Suggested useChew 2, 20 min before a meal
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What We Like

  • Unique gummy format activates DGL with saliva
  • Avoids bitter, chalky taste of traditional tablets
  • Free of common allergens and artificial additives
  • Potent 10:1 extract delivers 400 mg per serving

Trade-offs

  • Requires chewing two pieces before every meal

A 400 mg dose of a 10:1 DGL extract in a chocolate gummy is the main event here. It’s formulated for the person who finds chewable tablets unpleasant, turning a pre-meal ritual into something you might actually remember to do. The gummy format isn’t just a novelty; DGL is activated by saliva, so chewing makes pharmacological sense. This suits anyone with a consistent routine who prioritizes taste and compliance over sheer portability.

Enzymedica DGL Stomach Soothe Gummies come in a bottle that is taller than most chewable tablet competitors, so it demands more shelf space. This makes it a premium, user-friendly delivery system for daily use at home, not a discreet option for your travel bag. For a concentrated, no-fuss tablet you can take anywhere, Nature’s Way DGL Ultra Chewable Tablets present a slimmer alternative.

Best for: Individuals who dislike the taste of traditional DGL chewables and want a palatable, easy-to-comply-with daily regimen at home. Not ideal for frequent travelers or those seeking the most servings per container.

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#8Best Combination Formula

SFI Health CP7072 Dgl Supplement

SFI Health CP7072 Dgl Supplement
FormMastic Gum & DGL Chewable Tablets
FlavorCinnamon
Tablet Count60 Tablets
Allergen StatusHypoallergenic, no common allergens
Weight0.4 pounds
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What We Like

  • Unique mastic gum and DGL combination formula
  • Pleasant cinnamon-flavored chewable format
  • Free from major synthetic additives and allergens
  • Brand trusted by healthcare practitioners

Trade-offs

  • Only one flavor option, cinnamon

The inclusion of mastic gum alongside deglycyrrhizinated licorice makes this a dual-action formula aimed at broader digestive support, which is the core reason for its recognition here. It suits someone looking for a comprehensive, gentle herbal approach in a convenient chewable form, especially if they have sensitivities, given its clean, hypoallergenic build. The cinnamon flavor and tablet design make it a practical choice to keep on hand for after meals.

This chewable tablet combines mastic gum and DGL, a specific herbal pairing for digestive comfort not found in single-ingredient DGL supplements. The formula comes from a brand historically trusted by healthcare practitioners, which can provide confidence in its intended use. A cinnamon flavor makes the chewables pleasant to take without water after meals or at the first sign of upset.

Best for: Sensitive-system users seeking a dual-herb, chewable formula for general GI comfort. Not ideal for those wanting the highest possible single-ingredient DGL potency or the largest bottle size.

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#9Best Comprehensive Herbal Blend

Pure Encapsulations DGL Plus Capsules

Pure Encapsulations DGL Plus Capsules
Product NamePure Encapsulations DGL Plus Capsules
FormCapsules
Count60 Capsules
Key IngredientsDGL, aloe vera, marshmallow root, slippery elm
Allergen StatusFree from common allergens, GMOs, gluten
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What We Like

  • Comprehensive herbal blend with four supportive botanicals.
  • Vegan formula free from gluten and common allergens.
  • High-quality manufacturing with verified potency and purity.
  • Owner-reported effectiveness for soothing throat and acid reflux.

Trade-offs

  • Capsule form requires opening and mixing for optimal throat coating.
  • Earthy taste from powder can be unpleasant for some users.
  • Lacks the convenience of pre-flavored chewable alternatives.

Pure Encapsulations DGL Plus combines deglycyrrhizinated licorice with aloe vera, marshmallow root, and slippery elm bark for a multi-targeted approach to gastrointestinal support. This makes it a standout choice for someone seeking a comprehensive herbal regimen, particularly if they have sensitivities, as the formula avoids common allergens and unnecessary additives. Owner feedback specifically highlights its usefulness for relieving acid reflux and soothing throat irritation.

This capsule format requires a bit more effort to use. To get the full coating effect some people want, you must open the capsule and mix the powder with water, which introduces an earthy taste. A pre-flavored chewable like Nature’s Way DGL Ultra might be a better daily choice for convenience. This capsule is really for the detail-oriented user who doesn’t mind the extra step for a cleaner ingredient list.

Best for: Detail-oriented users seeking a comprehensive, allergen-free herbal blend for gastrointestinal support, who don't mind mixing a powder. Not ideal for those who prioritize quick, pleasant-tasting convenience above all else.

Product photos

#10Best Fructose-Free Option

Integrative Therapeutics Rhizinate Fructose Free

Integrative Therapeutics Rhizinate Fructose Free
Product FormChewable tablet
Tablet Count100 count
Glycyrrhizin ContentLess than 1%
Package Dimensions2.4 x 2.4 x 4.3 inches
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What We Like

  • Fructose-free chewable formula.
  • Contains no sugar, wheat, gluten, or soy.
  • Specifically formulated with less than 1% glycyrrhizin.
  • Manufacturer emphasizes quality and transparency.

Trade-offs

  • Shorter 100-count bottle versus 180-count options like Natural Factors.

The fructose-free formulation is the decisive feature here, making it a clear choice for anyone whose digestive comfort is disrupted by that specific sugar. It suits a buyer who needs a DGL supplement but is carefully managing their fructose intake, perhaps due to dietary sensitivities or a low-FODMAP protocol. The brand’s long-standing focus on quality and a clean label free from common allergens adds confidence for this specific user.

Planetary Herbals DGL comes in a notably compact bottle containing a hundred tablets, which is convenient for travel. The tradeoff is a smaller supply that requires more frequent reordering compared to a bulk bottle like Natural Factors’ 180-count. It’s a focused, specialty option. If fructose isn’t a concern, the standard Integrative Therapeutics Rhizinate chewable offers an identical count and brand trust in a slightly larger package.

Best for: Individuals seeking digestive comfort support who require a fructose-free and allergen-conscious formula. Not ideal for those prioritizing the highest tablet count per purchase.

Product photos

How We Evaluated DGL Supplements

Our evaluation was based on manufacturer specifications, independent testing reports, and patterns in expert round-ups and owner feedback. We prioritized the completeness of the deglycyrrhizination process, the convenience and compliance of the delivery format, and the overall value based on tablet count and formulation purity.

For example, we looked for products that specify a low glycyrrhizin content and those offering allergen-free, clean labels. This research-led approach means we cannot verify the exact glycyrrhizin levels in every bottle or guarantee individual results, but it highlights products with strong reputations and clear formulations.

What To Look For In DGL Supplements

Choosing a DGL supplement involves more than just picking a brand. You need to assess how well the product fits your lifestyle, supports your digestive goals, and meets quality standards. Our research into top DGL products and expert reviews points to three main criteria.

Key factors include verified low glycyrrhizin content, a convenient format you’ll actually use, and a formulation that aligns with your dietary needs and dosage preferences.

Glycyrrhizin Content

Glycyrrhizin is the compound in licorice root that can raise blood pressure. A true DGL supplement should have this compound removed. Look for products that explicitly state a low glycyrrhizin percentage, such as “less than 1%” or “glycyrrhizin-free.” Independent testing has found significant variation, with some products marketed as DGL containing higher-than-expected levels. Choosing a brand that transparently addresses this process is crucial for safety.

Delivery Format and Compliance

The format dictates how easily you’ll stick with the regimen. Chewable tablets are popular for their convenience and ability to mix with saliva, which may aid the soothing action. Gummies offer a palatable alternative for those who dislike herbal tastes. Capsules provide a precise dose but lack the direct coating action of a chewable or lozenge. Consider your routine: a product requiring pre-meal dosing multiple times a day demands more discipline than a once-daily option.

Formulation and Value

Examine the full ingredient list for additives, allergens, and supporting nutrients. Some formulas combine DGL with other soothing agents like slippery elm or mastic gum. Also, assess value by comparing the cost per serving and the total tablet count. A high-count bottle offers better long-term value for daily users but takes up more shelf space.

  • Check the label for common allergens like gluten, soy, dairy, or artificial sweeteners.
  • Note if the product is standardized to a specific extract, like GutGard, for more consistent potency.
  • Compare the serving size (e.g., one vs. Two tablets) to the total count to understand how long a bottle will last.

Choose a format you enjoy and a dosing schedule you can realistically maintain.

DGL Supplements Compared

For a quick side-by-side view of key features, the table below compares all ten picks.

ProductFormTablet CountDietary Features
Nature's Way DGL Ultra Chewable TabletsChocolate chewable tablet90Vegan, gluten-free, dairy-free
Natural Factors DGL Chewable Tabletschewable tablets180Vegan, non-GMO, free from major allergens
Planetary Herbals DGL Chewable TabletsChewable tablet100N/A
Integrative Therapeutics Rhizinate Chewable TabletsChewable Tablets100Vegan, Gluten-Free, Dairy-Free
Swanson DGL Chewable TabletsChewable tablet180Vegan, Vegetarian, Non-GMO
Designs for Health DGL Root ChewablesChewable90Gluten-Free, Vegetarian
Enzymedica DGL Stomach Soothe GummiesChocolate-flavored gummies74Vegan
SFI Health CP7072 Dgl SupplementChewable Tablets60Hypoallergenic, no common allergens
Pure Encapsulations DGL Plus CapsulesCapsules60Free from common allergens, GMOs, gluten
Integrative Therapeutics Rhizinate Fructose FreeChewable tablet100N/A

Frequently Asked Questions

Which brand of DGL is considered the best?

Our research points to Nature’s Way DGL Ultra Chewable Tablets as a top contender for most people due to its use of a standardized extract (GutGard), pleasant chocolate flavor, and clean formulation. However, “best” depends on your needs; for professional-strength, Planetary Herbals is a strong choice, while Natural Factors excels for high-count value.

Which DGL is the best?

The best DGL supplement is the one that effectively supports your digestive comfort while fitting easily into your routine. For a balanced combination of quality, taste, and convenience, the Nature’s Way DGL Ultra Chewable Tablets are a top choice. Different awards highlight options for specific needs like high potency or a gummy format.

Is it safe to take DGL every day?

When choosing a properly deglycyrrhizinated product with very low glycyrrhizin content, daily use is generally considered safe for periods of up to several months, according to expert guidelines. However, you should always consult with a healthcare provider before starting any new supplement regimen, especially if you have underlying health conditions.

Does DGL actually work?

Research and widespread owner feedback suggest DGL can support upper GI comfort by promoting the body’s own protective mucus production. Studies, while sometimes small-scale, indicate it may help improve symptoms of acid reflux and support mucosal lining health. It is often used as a strategic layer alongside dietary and lifestyle changes.

What’s the difference between DGL capsules and chewables?

Capsules provide a precise, tasteless dose but must be swallowed whole. Chewables and DGL gummies are designed to mix with saliva, which may help coat the throat and esophagus more directly. Chewables often include flavors to mask the herbal taste, which can improve compliance for those sensitive to it.

The Bottom Line

For a reliable, easy-to-take daily DGL supplement from a trusted brand, the Nature’s Way DGL Ultra Chewable Tablets are our top recommendation. If you’re on a budget and want the most servings per purchase, look to the Natural Factors DGL Chewable Tablets. For those seeking a professional-strength formula or a unique gummy format, the Planetary Herbals and Enzymedica picks are excellent alternatives. Ultimately, verifying low glycyrrhizin content and choosing a format you’ll use consistently are the most critical steps in finding an effective DGL supplement.